Substance
ID:180782
Names and Identifiers
IUPAC name
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC Traditional name
capsaicin
Synonyms
辣椒碱Capsaicin8-甲基-N-香草基-反-6-壬烯酰胺
Registration numbers
EC Number
CAS Number
Beilstein Number
MDL Number
PubChem SID
Properties
Safety Information
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RID/ADR
UN 2811 6.1/PG 2
UN Number
2811
Safety Statements
22-26-28-36/39-45
RTECS
RA8530000
Storage Temperature
2-8°C
Packing Group
2
European Hazard Symbols
Toxic (T)Risk Statements
25-37/38-41-42/43
Hazard Class
6.1
GHS Precautionary statements
P261-P280-P301+P310-P305+P351+P338-P342+P311
German water hazard class
3
GHS Hazard statements
H301-H315-H317-H318-H334-H335
Physical Property
Flash Point
113 °C
235.4 °F
Melting Point
62-65 °C(lit.)
Solubility
H2O: insoluble
ethanol: soluble
Pharmacology Properties
Gene Information
human ... CYP1A2(1544), TRPV1(7442)rat ... Trpv1(83810), Trpv4(66026)
Product Information
Biological Source
from Capsicum sp.
Purity
≥95%
Molecule Details
Frequently Asked Questions
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Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Molecular Spectra
No Data Available
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References
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