Substance
ID:180753
Names and Identifiers
IUPAC Traditional name
2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1H-pteridin-4-one
IUPAC name
2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4-dihydropteridin-4-one
Synonyms
2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine6-BiopterinL-erythro-6-(1,2-Dihydroxypropyl)pterin(1’R,2’S)-Biopterin
Registration numbers
CAS Number
MDL Number
Beilstein Number
PubChem SID
EC Number
Properties
Safety Information
European Hazard Symbols
Irritant (Xi)GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26-36
RTECS
UO3506000
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
German water hazard class
3
GHS Hazard statements
H315-H319-H335
Risk Statements
36/37/38
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Signal Word
Warning
Storage Temperature
2-8°C
Product Information
Purity
≥97%
Molecule Details
Application
6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.
6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.
Molecular Spectra
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References
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