Substance

ID:180694

5-Bromo-2′-deoxyuridine

Names and Identifiers
IUPAC Traditional name
5-bromo-2'-deoxyuridine
Synonyms
5-BrdU5-溴-2′-脱氧尿苷BUdR5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶5-溴脱氧尿苷5-Bromo-2′-deoxyuridine
IUPAC name
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Registration numbers
MDL Number
Beilstein Number
CAS Number
EC Number
PubChem SID
Properties
Product Information
Cation Traces
NH4+: ≤0.05%
Ca: ≤0.01%
K: ≤0.005%
Na: ≤0.05%
Al: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
Pb: ≤0.001%
Mg: ≤0.0005%
Zn: ≤0.0005%
Impurities
≤0.005% Phosphorus (P)
≤0.1% Insoluble matter
Ignition Residue
≤0.1%
Purity
≥99%
Safety Information
GHS Hazard statements
H340-H361
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
2
GHS Signal Word
Danger
RTECS
YU7350000
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Storage Temperature
-20°C
GHS Precautionary statements
P201-P281-P308+P313
Physical Property
Solubility
NH4OH: soluble0.1 M at 20 °C, clear, colorless
Melting Point
191-194 °C (dec.)(lit.)
Molecule Details
Frequently Asked Questions
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Biochem/physiol Actions
用作遗传研究中诱变剂的胸苷类似物。在 S 期可选择性结合到细胞 DNA 中。
Application
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Molecular Spectra
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References
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