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Substance
ID:180547
Structure
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Functional Group
Text
ID:132326
β-Amanitin from Amanita phalloides
Sigma Aldrich
ID: A1304
Names and Identifiers
Synonyms
β-Amanitin from Amanita phalloides
IUPAC Traditional name
β-amanitin
IUPAC name
2-[34-(butan-2-yl)-13-(3,4-dihydroxybutan-2-yl)-8,22-dihydroxy-2,5,11,14,27,30,33,36,39-nonaoxo-27λ
4
-thia-3,6,12,15,25,29,32,35,38-nonaazapentacyclo[14.12.11.0
6
,
1
0
.0
1
8
,
2
6
.0
1
9
,
2
4
]nonatriaconta-18(26),19,21,23-tetraen-4-yl]acetic acid
Registration numbers
MDL Number
MFCD00151212
EC Number
244-244-8
CAS Number
21150-22-1
PubChem SID
24890528
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Storage Temperature
-20°C
RID/ADR
UN 3462 6.1/PG 1
GHS Signal Word
Danger
Safety Statements
7
-
28
-
36/37/39
-
45
Hazard Class
6.1
Risk Statements
26/27/28
European Hazard Symbols
Highly toxic (T+)
Packing Group
1
RTECS
NJ8324000
GHS Precautionary statements
P260
-
P264
-
P280
-
P284
-
P302+P350
-
P310
GHS Hazard statements
H300
-
H310
-
H330
UN Number
3462
German water hazard class
3
Product Information
Purity
~90% (HPLC)
Molecule Details
Biochem/physiol Actions
Toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but not RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.
Molecular Spectra
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References
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