Substance
ID:180545
Names and Identifiers
IUPAC name
{[({[(5-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-7-yl}-3-hydroxyoxolan-2-yl)methoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}phosphonic acid
Synonyms
7-Deaza-2′-deoxyguanosine 5′-triphosphate lithium salt-N7-dGTP7-Deaza-dGTP
IUPAC Traditional name
{[(5-{2-amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7-yl}-3-hydroxyoxolan-2-yl)methoxy(hydroxy)phosphoryl]oxy(hydroxy)phosphoryl}oxyphosphonic acid
Properties
Product Information
Concentration
10 mM in H2O
Shipped in
dry ice
Safety Information
German water hazard class
2
Storage Temperature
-20°C
Molecule Details
Application
G residues can form secondary structures which are not fully denatured during electrophoresis. This can lead to sequence ambiguities. 7-Deaza-G doesn′t form these secondary structures, so avoids sequence ambiguities.
Biochem/physiol Actions
This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases.
G residues can form secondary structures which are not fully denatured during electrophoresis. This can lead to sequence ambiguities. 7-Deaza-G doesn′t form these secondary structures, so avoids sequence ambiguities.
Biochem/physiol Actions
This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases.
Molecular Spectra
No Data Available
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References
No Data Available
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