Substance
ID:180234
Names and Identifiers
IUPAC name
(3S)-3-{[(1S,2S)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-[(2S)-2-[(2R)-2-acetamido-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]propanoic acid
Synonyms
N-Acetyl-[D-Trp16]-Endothelin 1 fragment 16-21
IUPAC Traditional name
(3S)-3-{[(1S,2S)-1-{[(1S,2S)-1-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}-3-[(2S)-2-[(2R)-2-acetamido-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]propanoic acid
Properties
Safety Information
German water hazard class
3
Storage Temperature
-20°C
Product Information
Compostion
Dye content, ≥95% HPLC
Pharmacology Properties
Gene Information
human ... EDN1(1906)rat ... Ednra(24326), Ednrb(50672), Gnrhr(81668)
Molecule Details
Amino Acid Sequence
Ac-D-Trp-Leu-Asp-Ile-Ile-Trp
Biochem/physiol Actions
ETA antagonist; inhibits ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells.
Ac-D-Trp-Leu-Asp-Ile-Ile-Trp
Biochem/physiol Actions
ETA antagonist; inhibits ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells.
Molecular Spectra
No Data Available
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References
No Data Available
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