Substance
ID:179244
Names and Identifiers
IUPAC Traditional name
disulfiram
IUPAC name
N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide
Synonyms
二硫化四乙基秋兰姆TETDTetraethylthiuram disulfide双(二乙基硫代氨基甲酰)二硫化物双硫仑双硫醒
Registration numbers
EC Number
MDL Number
CAS Number
Beilstein Number
PubChem SID
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
European Hazard Symbols
Nature polluting (N)
Harmful (Xn)Hazard Class
9
GHS Signal Word
Warning
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RID/ADR
UN 3077 9/PG 3
German water hazard class
3
RTECS
JO1225000
Safety Statements
24-37-60-61
Risk Statements
22-43-48/22-50/53
UN Number
3077
Packing Group
3
GHS Precautionary statements
P273-P280-P501
GHS Hazard statements
H302-H317-H373-H410
Pharmacology Properties
Gene Information
human ... ALDH2(217), CYP1A2(1544)
Physical Property
Melting Point
69-71 °C(lit.)
Product Information
Purity
≥97%
Molecule Details
Application
乙醇脱氢酶抑制剂。
研究表明，双硫仑可作为原型，用于开发靶向 PKC 同工酶中氧化还原调控型 Cys 开关的新型防癌剂。Proceedings of the AACR，第45卷，2004 年 3 月。#2242
乙醇脱氢酶抑制剂。
研究表明，双硫仑可作为原型，用于开发靶向 PKC 同工酶中氧化还原调控型 Cys 开关的新型防癌剂。Proceedings of the AACR，第45卷，2004 年 3 月。#2242
Molecular Spectra
No Data Available
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References
No Data Available
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