Substance
ID:179162
Names and Identifiers
IUPAC name
3-bromo-7-nitro-1H-indazole
IUPAC Traditional name
3-bromo-7-nitroindazole
Synonyms
3-Bromo-7-nitroindazole
Properties
Physical Property
Apperance
light yellow powder
Solubility
ethanol: soluble25 mg/mL
DMSO: soluble
Safety Information
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
European Hazard Symbols
Toxic (T)GHS Precautionary statements
P201-P308+P313
German water hazard class
3
GHS Hazard statements
H360
Storage Temperature
2-8°C
GHS Signal Word
Danger
Risk Statements
60
Safety Statements
53-22-36/37/39-45
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Product Information
Purity
≥98% (TLC)
Molecule Details
Biochem/physiol Actions
A potent inhibitor of all nitric oxide synthase isoforms. Shows substantial neuroprotective effects against hypoxic damage (such as stroke) and animal models of Parkinsons disease. Crystallographic studies show that inhibition of eNOS is due to an induced cascade of conformation changes that ultimately dissociates the tetrahydrobiopterin cofactor from the enzyme.1
A potent inhibitor of all nitric oxide synthase isoforms. Shows substantial neuroprotective effects against hypoxic damage (such as stroke) and animal models of Parkinsons disease. Crystallographic studies show that inhibition of eNOS is due to an induced cascade of conformation changes that ultimately dissociates the tetrahydrobiopterin cofactor from the enzyme.1
Molecular Spectra
No Data Available
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References
No Data Available
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