Substance
ID:178932
Names and Identifiers
IUPAC name
5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one
IUPAC Traditional name
fluniβ
Synonyms
Flunitrazepam氟硝西泮Ro 5-42005-(2-Fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2(1H)-one
Properties
Pharmacology Properties
Gene Information
human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559)rat ... Gabra2(29706)
Safety Information
Drug Control
USDEA Schedule IV; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Signal Word
Warning
Risk Statements
22-36
Safety Statements
26-36
GHS Precautionary statements
P305+P351+P338
RTECS
DF2385000
GHS Hazard statements
H302-H319
European Hazard Symbols
Harmful (Xn)German water hazard class
2
Physical Property
Solubility
DMF: soluble
ethanol: soluble
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1 mg/mL
Molecule Details
Biochem/physiol Actions
Hypnotic; anxiolytic; ligand for the GABAA receptor benzodiazepine modulatory site.
Hypnotic; anxiolytic; ligand for the GABAA receptor benzodiazepine modulatory site.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data