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Substance
ID:178809
Structure
Similarity
Functional Group
Text
ID:3033
2-Mercaptoethanol
Sigma Aldrich
ID: M7154
Names and Identifiers
IUPAC Traditional name
β-mercaptoethanol
IUPAC name
2-sulfanylethan-1-ol
Synonyms
2-羟基乙硫醇
β-巯基乙醇
BME
硫代乙二醇
2-Mercaptoethanol
2-巯基乙醇
Registration numbers
CAS Number
60-24-2
EC Number
200-464-6
Beilstein Number
773648
MDL Number
MFCD00004890
PubChem SID
24897143
Properties
Safety Information
Explode Limits
18 %
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
European Hazard Symbols
Nature polluting (N)
Toxic (T)
RTECS
KL5600000
GHS Hazard statements
H301
-
H310+H330
-
H315
-
H317
-
H318
-
H410
Personal Protective Equipment
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
GHS Precautionary statements
P260
-
P273
-
P280
-
P284
-
P301+P310
-
P302+P350
Hazard Class
6.1
GHS Signal Word
Danger
UN Number
2966
Risk Statements
23/24/25
-
38
-
41
-
43
-
50/53
Safety Statements
26
-
36/37/39
-
45
-
60
-
61
RID/ADR
UN 2966 6.1/PG 2
Packing Group
2
Product Information
Cation Traces
Zn: <1 ppm
Fe: <1 ppm
Cu: <1 ppm
Pb: <5 ppm
Grade
for electrophoresis
Concentration
14.3 M (pure liquid)
Physical Property
Vapor Density
2.69 (vs air)
Boiling Point
157 °C(lit.)
Vapor Pressure
1 mmHg ( 20 °C)
Density
1.114 g/mL at 25 °C(lit.)
Flash Point
68 °C
154.4 °F
Refractive Index
n20/D 1.500(lit.)
Molecule Details
Application
BME 用于在聚丙烯酰胺凝胶电泳前还原蛋白质二硫键,通常以 5% 的浓度包含在用于 SDS-PAGE 的样本缓冲液中。裂解分子间(亚基之间)的二硫键,从而使蛋白质亚基在 SDS-PAGE 上各自分开。裂解分子内(亚基内)的二硫键从而使亚基完全变性,以便每个肽按照其链长迁移而不受二级结构的影响。
包装
25, 100 mL in glass bottle
Molecular Spectra
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References
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