Substance
ID:178722
Names and Identifiers
Synonyms
(E)-N-(3″-Phenylpropyl)-α-cyano-3′,5′-diisopropyl-4′-hydroxycinnamamideTyrphostin SU 1498
IUPAC Traditional name
(2E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)prop-2-enamide
IUPAC name
(2E)-2-cyano-3-[4-hydroxy-3,5-bis(propan-2-yl)phenyl]-N-(3-phenylpropyl)prop-2-enamide
Properties
Safety Information
Storage Temperature
-20°C
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant (Xi)GHS Signal Word
Warning
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26-36
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Risk Statements
36/37/38
Physical Property
Solubility
DMSO: soluble
Product Information
Potency
700 nM IC50
Purity
≥98%
Molecule Details
Biochem/physiol Actions
Potent and selective inhibitor of the VEGF receptor kinase, Flk-1. Very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase.
Potent and selective inhibitor of the VEGF receptor kinase, Flk-1. Very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data