Substance
ID:178721
Names and Identifiers
IUPAC name
{[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-methyloxolan-3-yl]oxy}phosphonic acid
IUPAC Traditional name
[(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-yl]oxyphosphonic acid
Synonyms
2′,5′-Dideoxy-3′-AMP2′,5′-dd-3′-AMP2′,5′-Dideoxyadenosine 3′-monophosphate
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Molecule Details
Biochem/physiol Actions
Potent inhibitor of adenylyl cyclase. Not cell-permeable. Precursor to 2′,5′-Dideoxyadenosine 3′-triphosphate (Prod. No. D0939). IC50 = 460 nM in detergent-dispersed rat brain preparation.
Potent inhibitor of adenylyl cyclase. Not cell-permeable. Precursor to 2′,5′-Dideoxyadenosine 3′-triphosphate (Prod. No. D0939). IC50 = 460 nM in detergent-dispersed rat brain preparation.
Molecular Spectra
No Data Available
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References
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