Substance
ID:178568
Names and Identifiers
IUPAC name
7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Synonyms
7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-oneDiazepamRo 5-2807地西泮
IUPAC Traditional name
diazepam
Properties
Safety Information
GHS Signal Word
Danger
GHS Precautionary statements
P280-P301+P310-P312
Packing Group
3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Class
6.1
German water hazard class
2
Drug Control
USDEA Schedule IV; Home Office Schedule 4.1; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
RID/ADR
UN 2811 6.1/PG 3
European Hazard Symbols
Harmful (Xn)Safety Statements
36/37
RTECS
DF1575000
Risk Statements
21/22
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Hazard statements
H301+H311
UN Number
2811
Physical Property
Solubility
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1.6 mg/mL
ethanol: soluble
H2O: slightly soluble
DMF: soluble
Pharmacology Properties
Gene Information
human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559)rat ... Gabra1(29705), Gabra2(29706)
Molecule Details
Biochem/physiol Actions
Benzodiazepine anxiolytic; prototype ligand for the GABAA receptor benzodiazepine modulatory site.
Benzodiazepine anxiolytic; prototype ligand for the GABAA receptor benzodiazepine modulatory site.
Molecular Spectra
No Data Available
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References
No Data Available
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