Substance
ID:178482
Names and Identifiers
IUPAC name
6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridine-3-carbonitrile
IUPAC Traditional name
milrinone
Synonyms
1,6-Dihydro-2-methyl-6-oxo-(3,4′-bipyridine)-5-carbonitrileMilrinone
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS
DW1762000
UN Number
2811
RID/ADR
UN 2811 6.1/PG 3
GHS Hazard statements
H301-H311-H331
European Hazard Symbols
Toxic (T)Packing Group
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Hazard Class
6.1
German water hazard class
3
Risk Statements
23/24/25
Storage Temperature
2-8°C
GHS Signal Word
Danger
GHS Precautionary statements
P261-P280-P301+P310-P311
Safety Statements
36/37/39-45
Physical Property
Apperance
off-white powder
Solubility
H2O: insoluble
DMSO: >10 mg/mL
Product Information
Purity
≥97% (TLC)
Pharmacology Properties
Gene Information
human ... PDE3A(5139), PDE3B(5140), PDE4B(5142), PDE5A(8654), PTPRA(5786)rat ... Pde3a(50678)
Molecule Details
Biochem/physiol Actions
Phosphodiesterase type III inhibitor; cAMP-specific, cGMP-inhibitable; potent cardiotonic, positive inotropic vasodilator.
Phosphodiesterase type III inhibitor; cAMP-specific, cGMP-inhibitable; potent cardiotonic, positive inotropic vasodilator.
Molecular Spectra
No Data Available
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References
No Data Available
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