Substance
ID:178258
Names and Identifiers
IUPAC name
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC Traditional name
capsaicin
Synonyms
辣椒碱Capsaicin8-甲基-N-香草基-反-6-壬烯酰胺
Registration numbers
EC Number
CAS Number
Beilstein Number
MDL Number
Properties
Safety Information
GHS Signal Word
Danger
GHS Hazard statements
H301-H315-H317-H318-H334-H335
RTECS
RA8530000
Hazard Class
6.1
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
RID/ADR
UN 2811 6.1/PG 2
GHS Precautionary statements
P261-P280-P301+P310-P305+P351+P338-P342+P311
Storage Temperature
2-8°C
UN Number
2811
Risk Statements
25-37/38-41-42/43
Packing Group
2
German water hazard class
3
European Hazard Symbols
Toxic (T)Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
22-26-28-36/39-45
Physical Property
Flash Point
235.4 °F
113 °C
Melting Point
62-65 °C(lit.)
Product Information
Purity
~60%
Molecule Details
Quality
Contains approx. 30% dihydrocapsaicin, balance other naturally occurring capsaicinoids.
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Contains approx. 30% dihydrocapsaicin, balance other naturally occurring capsaicinoids.
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Molecular Spectra
No Data Available
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References
No Data Available
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