Substance
ID:178134
Names and Identifiers
IUPAC name
5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol
IUPAC Traditional name
mazindol
Synonyms
5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-olMazindol
Properties
Pharmacology Properties
Gene Information
human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)rat ... Htr1a(24473), Htr2a(29595), Slc6a3(24898), Slc6a4(25553)
Physical Property
Solubility
DMSO: soluble10 mg/mL
Apperance
white powder
Safety Information
RTECS
NI2975000
UN Number
2811
Drug Control
USDEA Schedule IV; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
European Hazard Symbols
Toxic (T)Hazard Class
6.1
German water hazard class
3
RID/ADR
UN 2811 6.1/PG 2
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Risk Statements
23/24/25
Safety Statements
36/37/39-45
Packing Group
2
GHS Hazard statements
H300-H311-H331
GHS Precautionary statements
P261-P264-P280-P301+P310-P311
Product Information
Purity
≥98% (TLC)
Molecule Details
Biochem/physiol Actions
Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters with Kis of 27.6 nM, 3.2 nM, and 153 nM, respectively.
Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters with Kis of 27.6 nM, 3.2 nM, and 153 nM, respectively.
Molecular Spectra
No Data Available
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References
No Data Available
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