Substance
ID:178134
Names and Identifiers
IUPAC name
5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol
IUPAC Traditional name
mazindol
Synonyms
5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-olMazindol
Properties
Safety Information
Safety Statements
36/37/39-45
Drug Control
USDEA Schedule IV; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
German water hazard class
3
GHS Signal Word
Danger
Hazard Class
6.1
GHS Hazard statements
H300-H311-H331
UN Number
2811
European Hazard Symbols
Toxic (T)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS
NI2975000
Packing Group
2
Risk Statements
23/24/25
GHS Precautionary statements
P261-P264-P280-P301+P310-P311
RID/ADR
UN 2811 6.1/PG 2
Physical Property
Apperance
white powder
Solubility
DMSO: soluble10 mg/mL
Pharmacology Properties
Gene Information
human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)rat ... Htr1a(24473), Htr2a(29595), Slc6a3(24898), Slc6a4(25553)
Product Information
Purity
≥98% (TLC)
Molecule Details
Biochem/physiol Actions
Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters with Kis of 27.6 nM, 3.2 nM, and 153 nM, respectively.
Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters with Kis of 27.6 nM, 3.2 nM, and 153 nM, respectively.
Molecular Spectra
No Data Available
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References
No Data Available
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