Substance
ID:177839
Names and Identifiers
IUPAC name
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC Traditional name
tetracycline hydrochloride
Synonyms
四环素 盐酸盐Tetracycline hydrochloride
Registration numbers
EC Number
CAS Number
MDL Number
Beilstein Number
PubChem SID
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
RTECS
QI9100000
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
German water hazard class
2
European Hazard Symbols
Irritant (Xi)Storage Temperature
-20°C
GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
GHS Hazard statements
H315-H319-H335
Risk Statements
36/37/38
Safety Statements
26-36
Physical Property
Melting Point
220-223 °C(lit.)
Apperance
powder
Product Information
Sterility
γ-irradiated
Molecule Details
Application
建议以 10-20μg/ml 的量用于分子生物学应用。
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Reconstitution
直接在样品瓶中用无菌水 (10mg/ml) 制备储存液。储存液在 2-8°C 下保存不应超过一周；四环素在水溶液中会发生水解。
建议以 10-20μg/ml 的量用于分子生物学应用。
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Reconstitution
直接在样品瓶中用无菌水 (10mg/ml) 制备储存液。储存液在 2-8°C 下保存不应超过一周；四环素在水溶液中会发生水解。
Molecular Spectra
No Data Available
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References
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