Substance
ID:177788
Names and Identifiers
Synonyms
奎宁 硫酸酯Quinine sulfate (2:1) (salt) dihydrate奎宁 半硫酸盐 一水合物Quinine sulfate
IUPAC Traditional name
bis(quinine) sulfuric acid dihydrate
IUPAC name
bis((R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol) sulfuric acid dihydrate
Registration numbers
Beilstein Number
CAS Number
MDL Number
PubChem SID
Properties
Safety Information
GHS Precautionary statements
P261-P305+P351+P338
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
26
Risk Statements
36/37/38
GHS Hazard statements
H315-H319-H335
GHS Signal Word
Warning
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Irritant (Xi)Product Information
Mol. Weight
monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)
Suitability
meets USP testing specifications
Physical Property
Melting Point
~225 °C (dec.)(lit.)
Molecule Details
Application
Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.
Biochem/physiol Actions
钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂；最初从南美树木的金鸡纳科中分离出来的生物碱。
Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.
Biochem/physiol Actions
钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂；最初从南美树木的金鸡纳科中分离出来的生物碱。
Molecular Spectra
No Data Available
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References
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