Substance
ID:177785
Names and Identifiers
IUPAC Traditional name
kanamycin; sulfuric acid
IUPAC name
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
Synonyms
卡那霉素 A卡那霉素碱 硫酸盐Kanamycin sulfate from Streptomyces kanamyceticus卡那霉素 硫酸酯 来源于卡那霉素链霉菌
Properties
Safety Information
European Hazard Symbols
Toxic (T)GHS Hazard statements
H360
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Risk Statements
61
RTECS
NZ3225030
Safety Statements
53-45
GHS Precautionary statements
P201-P308+P313
GHS Signal Word
Danger
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
German water hazard class
2
Product Information
Potency
≥750 μg per mg
Quality Level
PREMIUM
Suitability
meets USP testing specifications
Physical Property
Apperance
powder
Solubility
H2O: soluble10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)
Molecule Details
Application
Used in biotechnology applications to inhibit protein synthesis. Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene.
Biochem/physiol Actions
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.
Used in biotechnology applications to inhibit protein synthesis. Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene.
Biochem/physiol Actions
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data