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Substance
ID:177752
Structure
Similarity
Functional Group
Text
ID:68131
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
Sigma Aldrich
ID: E1769
Names and Identifiers
Synonyms
EDC 盐酸盐
N-乙基-N′-(3-二甲基氨丙基)碳二亚胺 盐酸盐
1-(3-二甲氨基丙基)-3-乙基碳二亚胺 盐酸盐
WSC 盐酸盐
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
EDAC
IUPAC name
(3-{[(ethylimino)methylidene]amino}propyl)dimethylamine hydrochloride
IUPAC Traditional name
(3-{[(ethylimino)methylidene]amino}propyl)dimethylamine hydrochloride
Registration numbers
CAS Number
25952-53-8
Beilstein Number
5764110
EC Number
247-361-2
MDL Number
MFCD00012503
PubChem SID
24894433
Properties
Product Information
Cation Traces
K: ≤0.005%
Fe: ≤0.0005%
Al: ≤0.0005%
Ca: ≤0.0005%
Na: ≤0.005%
Pb: ≤0.001%
NH4+: ≤0.05%
Cu: ≤0.0005%
Mg: ≤0.0005%
Zn: ≤0.0005%
Ignition Residue
≤0.1%
Impurities
≤0.005% Phosphorus (P)
≤0.1% Insoluble matter
Antion Traces
sulfate (SO42-): ≤0.05%
Safety Information
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Irritant (Xi)
GHS Signal Word
Danger
GHS Hazard statements
H315
-
H318
-
H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
37/38
-
41
Storage Temperature
-20°C
RTECS
FF2200000
GHS Precautionary statements
P261
-
P280
-
P305+P351+P338
Safety Statements
26
-
36/37/39
German water hazard class
3
Physical Property
Melting Point
110-115 °C(lit.)
Solubility
H2O: soluble0.5 M, clear, colorless
Molecule Details
Biochem/physiol Actions
水溶性缩合剂。常用作酰胺与伯胺键合的羧基活化剂。此外,它可与磷酸基团反应。可用于例如肽合成;蛋白质和核酸的交联;以及免疫交联物的制备。通常,在无缓冲液的条件下,其工作 pH 范围为 4.0-6.0。应特别避免胺和羧酸盐缓冲液。
Molecular Spectra
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References
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