Substance
ID:177603
Names and Identifiers
IUPAC Traditional name
N-ethylmaleimide
IUPAC name
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
Synonyms
NEMN-EthylmaleimideN-乙基马来酰亚胺
Registration numbers
MDL Number
CAS Number
EC Number
PubChem SID
Beilstein Number
Properties
Product Information
Antion Traces
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
Cation Traces
K: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
Na: ≤0.005%
Pb: ≤0.001%
Ca: ≤0.0005%
Mg: ≤0.0005%
Al: ≤0.0005%
Zn: ≤0.0005%
Purity
≥98% (HPLC)
Impurities
≤0.001% Phosphorus (P)
≤0.1% Insoluble matter
Ignition Residue
≤0.1%
Safety Information
GHS Signal Word
Danger
GHS Hazard statements
H300-H311-H314-H317
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS
UX9625000
Hazard Class
6.1
UN Number
2928
German water hazard class
3
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Packing Group
2
GHS Precautionary statements
P264-P280-P301+P310-P305+P351+P338-P310
Safety Statements
26-28-36/37/39-45
European Hazard Symbols
Highly toxic (T+)RID/ADR
UN 2928 6.1/PG 2
Risk Statements
21-28-34-43
Storage Temperature
2-8°C
Physical Property
Flash Point
73 °C
163.4 °F
Melting Point
43-46 °C(lit.)
Boiling Point
210 °C(lit.)
Solubility
95% ethanol: soluble50 mg/mL, clear to slightly hazy (colorless to faint yellow)
Pharmacology Properties
Gene Information
human ... SLC6A3(6531), SLC6A4(6532)
Molecule Details
Application
用于共价修饰蛋白质的半胱氨酸残基的试剂。
Biochem/physiol Actions
使 NADP 依赖性异柠檬酸脱氢酶和许多核酸内切酶失活的巯基烷化剂。
增强来自交感神经元的原生 M 通道的电流，并作为 KCNQ2、KCNQ4 和 KCNQ5 通道的开放剂。
用于共价修饰蛋白质的半胱氨酸残基的试剂。
Biochem/physiol Actions
使 NADP 依赖性异柠檬酸脱氢酶和许多核酸内切酶失活的巯基烷化剂。
增强来自交感神经元的原生 M 通道的电流，并作为 KCNQ2、KCNQ4 和 KCNQ5 通道的开放剂。
Molecular Spectra
No Data Available
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References
No Data Available
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