Substance
ID:177508
Names and Identifiers
IUPAC Traditional name
griseofulvin
Synonyms
(2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione灰黄霉素Griseofulvin
IUPAC name
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
Registration numbers
MDL Number
EC Number
Beilstein Number
PubChem SID
CAS Number
Properties
Product Information
Biological Source
from Penicillium griseofulvum
Suitability
meets USP testing specifications
Safety Information
Storage Temperature
-20°C
German water hazard class
3
GHS Signal Word
Danger
GHS Precautionary statements
P201-P280-P308+P313
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Toxic (T)Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS
WG9800000
GHS Hazard statements
H317-H351-H360
Risk Statements
60-61-40-43
Safety Statements
22-36/37/39-45
Molecule Details
Biochem/physiol Actions
Griseofulvin disrupts microtubule assembly and mitotic spindle stucture possibly via tubulin aggregation.
Griseofulvin disrupts microtubule assembly and mitotic spindle stucture possibly via tubulin aggregation.
Molecular Spectra
No Data Available
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References
No Data Available
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