Substance
ID:177445
Names and Identifiers
IUPAC name
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
IUPAC Traditional name
norfloxacin
Synonyms
诺氟沙星1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸1-乙基-6-氟-1,4-二氢-4-氧代-7-哌嗪-3-喹啉羧酸Norfloxacin
Properties
Safety Information
German water hazard class
2
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
2-8°C
RTECS
VB2005000
Product Information
Purity
≥98% (TLC)
Suitability
suitable for 1694 per US EPA
Pharmacology Properties
Gene Information
human ... CYP1A2(1544)rat ... Gabra1(29705)
Molecule Details
Biochem/physiol Actions
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
Molecular Spectra
No Data Available
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References
No Data Available
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