Substance

ID:176849

Names and Identifiers
Synonyms
Sirolimus
IUPAC name
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28Z,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
IUPAC Traditional name
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28Z,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Registration numbers
CHEBI ID
CHEMBL
Wikipedia Title
Chemspider ID
KEGG ID
DrugBank ID
PubChem CID
Unique Ingredient Identifier
ATC CODE
CAS Number
Properties
Pharmacology Properties
Half Life
57–63 hours
US Licence
Sirolimus
Bioavailability
20%, less after eating food rich in fat
Admin Routes
Oral
Excretion
Mostly faecal
EU Licence
Rapamune
Legal Status
Rx-only (US)
Pregnancy Category
C (US)
C (Australia)
Metabolism
Hepatic
Protein Bound
92%
Molecule Details
Molecular Spectra
No Data Available
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References
No Data Available
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