Substance

ID:176841

Names and Identifiers
Synonyms
Amphotericin B
IUPAC Traditional name
amphotericin B
IUPAC name
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Brand Name
Fungizone
Registration numbers
Chemspider ID
10237579
DrugBank ID
DB00681
CAS Number
1397-89-3
KEGG ID
D00203
CHEMBL
267345
PubChem CID
14956
Wikipedia Title
Amphotericin_B
CHEBI ID
2682
Properties
Pharmacology Properties
Half Life
initial phase : 24 hours,
second phase : approx. 15 days
Pregnancy Category
B (US)
Admin Routes
slow i.v.-infusion only
Bioavailability
100% (IV)
Legal Status
Rx-only, hospitalization recommended.
Metabolism
renal
Excretion
40% found in urine after single cumulated over several days
biliar excretion also important
Molecule Details
Molecular Spectra
No Data Available
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References
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