Substance

ID:176674

Names and Identifiers
IUPAC name
(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
Synonyms
Paroxetine
Brand Name
Paxil, Pexeva
IUPAC Traditional name
paroxetine
Registration numbers
Chemspider ID
39888
KEGG ID
D02362
PubChem CID
43815
CHEMBL
490
DrugBank ID
DB00715
Medline Plus
a698032
Unique Ingredient Identifier
41VRH5220H
CHEBI ID
7936
CAS Number
61869-08-7
Wikipedia Title
Paroxetine
ATC CODE
N06AB05
Properties
Pharmacology Properties
Admin Routes
Oral
Bioavailability
Completely absorbed from GI, but extensive first-pass metabolism in the liver; Tmax 4.9 (with meals) to 6.4 hours (fasting)
Protein Bound
93–95%
Excretion
64% in urine, 36% in bile
Legal Status
Rx-only
Half Life
24 hours (range 3–65 hours)
US Licence
Paroxetine
Metabolism
Extensive, hepatic (mostly CYP2D6-mediated)
Pregnancy Category
D (US)
Molecule Details
Molecular Spectra
No Data Available
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References
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