Substance

ID:172064

Names and Identifiers
IUPAC Traditional name
febuxostat
Synonyms
Febuxostat
IUPAC name
2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Brand Name
Adenuric, Uloric , Febutaz
Registration numbers
Wikipedia Title
Febuxostat
ATC CODE
M04AA03
CAS Number
144060-53-7
Medline Plus
a609020
KEGG ID
D01206
PubChem CID
134018
CHEMBL
1164729
Chemspider ID
118173
Unique Ingredient Identifier
101V0R1N2E
Properties
Pharmacology Properties
Excretion
urine (~49% mostly as metabolites, 3% as unchanged drug); feces (~45% mostly as metabolites, 12% as unchanged drug)
Metabolism
via CYP1A2, 2C8, 2C9, UGT1A1, 1A3, 1A9, 2B7
Half Life
~5-8 hours
EU Licence
Adenuric
Protein Bound
~99% to albumin
Pregnancy Category
C
Admin Routes
oral
Bioavailability
~49% absorbed
Legal Status
Rx-only (US)
US Licence
Febuxostat
Molecule Details
Molecular Spectra
No Data Available
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References
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