C (US)

Moderate

17% to 36%

Oral, insufflation, enema

urine (100%)

5 hours

unscheduled (Australia)

GSL (UK)

OTC (US)

99%

demethylation by CYP1A2

227–228 °C, 500-501 K (anhydrous)
234–235 °C, 507-508 K (monohydrate)

178°C (subl.)

Odorless, white needles or powder

1.23 g/cm³, solid

-0.13–1.22 protonated caffeine

2.17 g/100 mL (25 °C)
18.0 g/100 mL (80 °C)
67.0 g/100 mL (100 °C) in water

3.64 D (calculated)

613-086-00-5

S2

Harmful (Xn)

192 mg/kg (rat, oral)

R22

EV6475000