Substance

ID:170352

Names and Identifiers
IUPAC Traditional name
buprenorphine
Brand Name
Buprenex, Subutex, Suboxone, Butrans
IUPAC name
(1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10-trien-11-ol
Synonyms
Buprenorphine
Registration numbers
CAS Number
52485-79-7
CHEBI ID
3216
KEGG ID
D07132
DrugBank ID
DB00921
IUPHAR ligand ID
1670
Unique Ingredient Identifier
40D3SCR4GZ
Chemspider ID
559124
PubChem CID
644073
CHEMBL
1201894
Medline Plus
a605002
Wikipedia Title
Buprenorphine
Properties
Pharmacology Properties
Excretion
biliary and renal
Protein Bound
96%
Half Life
20–70, mean 37 hours
Pregnancy Category
C (USA)
Legal Status
Schedule III (V some states) (USA)
Schedule 8 (Aust)
Class C(UK)
Cat. A Singapore
Schedule III Germany
Metabolism
hepatic
CYP3A4, CYP2C8
Bioavailability
55%(sublingual)/48.2% +/- 8.35%(intranasal)
Admin Routes
sublingual, IM, IV, transdermal, intranasal, rectallyon
Molecule Details
Molecular Spectra
No Data Available
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References
No Data Available
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