Substance

ID:169918

Names and Identifiers
Synonyms
Azathioprine
IUPAC Traditional name
azathioprine
IUPAC name
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
Brand Name
Azasan, Imuran and others
Registration numbers
CAS Number
446-86-6
PubChem CID
2265
Chemspider ID
2178
Medline Plus
a682167
Unique Ingredient Identifier
MRK240IY2L
CHEBI ID
2948
KEGG ID
D00238
Wikipedia Title
Azathioprine
ATC CODE
L04AX01
CHEMBL
1542
DrugBank ID
DB00993
Properties
Pharmacology Properties
Bioavailability
60±31%
Pregnancy Category
D (Australia)
D (US)
Admin Routes
Mainly oral (sometimes initially intravenous)
Metabolism
Activated non-enzymatically, deactivated mainly by xanthine oxidase
Half Life
26–80 minutes (azathioprine)
3–5 hours (drug plus metabolites)
Protein Bound
20–30%
Legal Status
Rx-only
US Licence
azathioprine
Excretion
Renal, 98% as metabolites
Physical Property
Melting Point
238-245 °C (460.4-473°F)
Molecule Details
Molecular Spectra
No Data Available
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References
No Data Available
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