Substance

ID:138

Names and Identifiers
IUPAC Traditional name
medrysone
IUPAC name
(1S,2R,8S,10S,11S,14S,15S,17S)-14-acetyl-17-hydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
Brand Name
HMS LiquifilmMedrifarMedritonicMedrocortHMSVisudrisone
Synonyms
MedrysoneHydroxymesterone
Registration numbers
CAS Number
PubChem CID
PubChem SID
Properties
Physical Property
Hydrophobicity(logP)
3.2
Molecule Details
Drug Groups
approved
Description
Medrysone is a corticosteroid used in ophthalmology. [Wikipedia]
Indication
For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.
Pharmacology
Medrysone is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.
Affected Organisms
Humans and other mammals
Absorption
Rapidly absorbed following oral administration.
External Links
Molecular Spectra
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References
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