Substance
ID:130935
Names and Identifiers
Synonyms
Ac-Val-Asp-Val-Ala-Asp-PNAAc-Val-Asp-Val-Ala-Asp-paranitroanilideAc-VDVAD-PNA
IUPAC name
(3S)-3-{[(1S)-1-{[(1S)-1-{[(1S)-2-carboxy-1-[(4-nitrophenyl)carbamoyl]ethyl]carbamoyl}ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-[(2S)-2-acetamido-3-methylbutanamido]propanoic acid
IUPAC Traditional name
(3S)-3-{[(1S)-1-{[(1S)-1-{[(1S)-2-carboxy-1-[(4-nitrophenyl)carbamoyl]ethyl]carbamoyl}ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-[(2S)-2-acetamido-3-methylbutanamido]propanoic acid
Registration numbers
No Data Available
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Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A colorimetric substrate for detection of Caspase-2 (ICH-1). Cleavage is monitored colorimetrically at ~405 nm.
Molecular Spectra
No Data Available
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References
• Thornberry, N.A. et al., Science, 281:1312 (1998).
• Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.