Substance
ID:130832
Names and Identifiers
Synonyms
Z-Val-Ala-Asp-FluoromethylketoneZ-Val-Ala-Asp-FMKZ-VAD-FMK
IUPAC Traditional name
(3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic acid
IUPAC name
(3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic acid
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
An irreversible general caspase inhibitor, non-methylated form.PROTECT FROM MOISTURE. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Z-VAD(OMe)-FMK (Cat. No. FK009), this inhibitor does not require pretreatment with esterase for in vitro studies.
Molecular Spectra
No Data Available
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References
• Komoriya, A. et al., J. Exp. Med., 191:1819 (2000).
• Weissner, C. et al., Cell. Mol. Biol., 46:53 (2000).
• Misaghi, S., et al. 2004. Chem. Biol. 11, 1677.