Substance
ID:130825
Names and Identifiers
Synonyms
Z-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-FMKZ-LE(OMe)E(OMe)D(OMe)-FMKZ-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-Fluoromethylketone
IUPAC name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-5-methoxy-5-oxopentanamido]-5-methoxy-5-oxopentanamido]-5-fluoro-4-oxopentanoate
IUPAC Traditional name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-5-methoxy-5-oxopentanamido]-5-methoxy-5-oxopentanamido]-5-fluoro-4-oxopentanoate
Registration numbers
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Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A cell-permeable, irreversible inhibitor of caspase-13. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
Molecular Spectra
No Data Available
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References
• Humke, E.W. et al., J. Biol. Chem., 273(25):15702 (1998).