Substance
ID:130819
Names and Identifiers
IUPAC Traditional name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methoxy-4-oxobutanamido]-4-carbamoylbutanamido]-4-(methylsulfanyl)butanamido]-5-fluoro-4-oxopentanoate
Synonyms
Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMKZ-D(OMe)QMD(OMe)-FMKZ-Asp(OMe)-Gln-Met-Asp(OMe)-Fluoromethylketone
IUPAC name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methoxy-4-oxobutanamido]-4-carbamoylbutanamido]-4-(methylsulfanyl)butanamido]-5-fluoro-4-oxopentanoate
Registration numbers
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Properties
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Molecule Details
A potent, cell-permeable, and irreversible inhibitor of caspase-3, also recognizes caspase-1. When using with purified native or recombinant enzyme, pre-treatment with an esterase is required.
Molecular Spectra
No Data Available
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References
• Hirata, H. et al., J. Exp. Med., 187(4):587(1998).
• Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.