Substance
ID:130810
Names and Identifiers
Synonyms
Z-VD(OMe)VAD(OMe)-FMKZ-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMKZ-Val-Asp(OMe)-Val-Ala-Asp(OMe)-Fluoromethylketone
IUPAC name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
IUPAC Traditional name
methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
Registration numbers
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Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1)
Molecular Spectra
No Data Available
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References
• Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
• Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
• Zhuang, S. et al., Am. J. Physiol. Cell. Physiol., 279(2):C341 (2000).
• Talanian, R.V. et al., J. Biol. Chem., 272(15):9677 (1997).