Substance
ID:130809
Names and Identifiers
IUPAC name
methyl (3S)-3-[(2S,3S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-5-methoxy-5-oxopentanamido]-3-methylpentanamido]-5-fluoro-4-oxopentanoate
Synonyms
Z-Val-Glu(OMe)-Ile-Asp(OMe)-FluoromethylketoneZ-Val-Glu(OMe)-Ile-Asp(OMe)-FMKZ-VE(OMe)ID(OMe)-FMK
IUPAC Traditional name
methyl (3S)-3-[(2S,3S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-5-methoxy-5-oxopentanamido]-3-methylpentanamido]-5-fluoro-4-oxopentanoate
Registration numbers
No Data Available
Click here to submit data
Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A cell-permeable, irreversible inhibitor of caspase-6. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
Molecular Spectra
No Data Available
Click here to submit data
References
• Zhuang, S. et al., Am. J. Physiol. Cell. Physiol., 279(2):C341 (2000).
• Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
• Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.