Substance
ID:130808
Names and Identifiers
Synonyms
Biotin-VAD(OMe)-FMKBiotin-Val-Ala-Asp(OMe)-FluoromethylketoneBiotin-Val-Ala-Asp(OMe)-FMK
IUPAC Traditional name
methyl (3S)-3-[(2S)-2-[(2S)-2-(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydrothieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanamido)-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
IUPAC name
methyl (3S)-3-[(2S)-2-[(2S)-2-(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanamido)-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
Registration numbers
No Data Available
Click here to submit data
Properties
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Molecule Details
An inhibitor/probe for General Caspases. Biotinylated derivative of Z-VAD(OMe)-FMK that may be used to identify active caspases in cell lysates. There is a linker molecule (epsilon-AMINO-N-CAPROIC ACID) between biotin and the peptide.
Molecular Spectra
No Data Available
Click here to submit data
References
• Bombeck, C.A. et al., J. Biol. Chem., 274(24):17325 (1999).
• Li, S. et al. 1999. J. Biol. Chem. 274, 17325.
• Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.