Substance
ID:129375
Names and Identifiers
IUPAC name
(1S,2R,5S,7R,11S,14S)-11-hydroxy-7-(2-hydroxypropan-2-yl)-1,2-dimethyl-6-oxa-23-azahexacyclo[12.10.0.0?,??.0?,??.0??,??.0??,??]tetracosa-9,16(24),17,19,21-pentaen-8-one
IUPAC Traditional name
paxilline
Synonyms
PAXILLINE
Registration numbers
CAS Number
Properties
Safety Information
Product Information
Certificate of Analysis
Molecule Details
From Penicillium paxilli
This fungal mycotoxin possess potent excitatory action on acetylcholine release from nerve terminals. It specifically inhibits smooth muscle high conductance Ca2+ -activated K+ channels, as well as, enhances [125 I]-charybotoxin binding to these channels.
This fungal mycotoxin possess potent excitatory action on acetylcholine release from nerve terminals. It specifically inhibits smooth muscle high conductance Ca2+ -activated K+ channels, as well as, enhances [125 I]-charybotoxin binding to these channels.
Molecular Spectra
No Data Available
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References
• Knaus, et al., Biochemistry , 33 : 5819 (1994).