Substance
ID:128571
Names and Identifiers
IUPAC name
5-hydroxy-4-{6-hydroxy-5-[4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hex-3-en-1-yl]-3,6-dihydro-2H-pyran-2-yl}-2,5-dihydrofuran-2-one
IUPAC Traditional name
manoalide
Synonyms
MANOALIDE
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Purity
≥95%
Safety Information
Storage Condition
-20°C
MSDS Link
Molecule Details
From Luffariella variabilis
Purity: >95%
Phospholipase A2 and C inhibitor. Also blocks the release of arachidonate and inhibits calcium channels.
Purity: >95%
Phospholipase A2 and C inhibitor. Also blocks the release of arachidonate and inhibits calcium channels.
Molecular Spectra
No Data Available
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References
• Wheeler, L.A., et al., J. Biol. Chem. , 262 : 6531, (1987).
• Glaser, K.B. and Jacobs, R.S., ibid. , 36 : 2079, (1987).
• Lombardo, D. and Dennis, E.A., J. Biol. Chem. , 260 : 7234, (1985).
• Bennertt, C., et al., Pharmacologist , 28 : 538, (1986)
• Mayer, A.M.S., et al., J. Pharm. Exp. Ther. , 244 : 871, (1988).
• Jacobson, P.B., et al., Biochem. Pharmacol. , 39 : 1557, (1990).