Substance

ID:1269

Names and Identifiers
Synonyms
Fencamfamina [dcit]FencamfamineFencamfamine hydrochloride2-Aethylamino-3-phenyl-nor-camphanFencamfamine [inn-french]Fencanfamina [inn-spanish]2-Ethylamino-3-phenylnorcamphane hydrochloride2-Ethylamino-3-phenyl-norcamphane hydrochlorideFencamfaminum [inn-latin]FencamfaminFencamfamin hydrochloride
IUPAC Traditional name
fencamfamine
Brand Name
GlucoenerganReactivanEuvitol
IUPAC name
N-ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine
Registration numbers
CAS Number
PubChem SID
PubChem CID
Properties
Physical Property
Hydrophobicity(logP)
3.20 [SANGSTER (1994)]
Molecule Details
Drug Groups
illicit; approved; withdrawn
Description
Fencamfamine (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Reactivan is still rarely used for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases. [Wikipedia]
Indication
For the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
Pharmacology
Fencamfamine increases drive and mental alertness and an elevation of mood and a general feeling of well-being. It is a central nervous system stimulant, which increases locomotor activity.
Toxicity
Overdosage is characterised by nausea, agitation and restlessness, dryness of the mouth, dizziness and tremor. In gross overdosage the above symptoms may also be associated with dyspnoea, tachycardia, disorientation and convulsions.
Affected Organisms
Humans and other mammals
References
• DeLucia R, Planeta CS: Fencamfamine. Gen Pharmacol. 1990;21(2):161-3. [Pubmed]
External Links
Molecular Spectra
No Data Available
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References
•  Link
• DeLucia R, Planeta CS: Fencamfamine. Gen Pharmacol. 1990;21(2):161-3. Pubmed