Substance
ID:1245
Names and Identifiers
Synonyms
Almitrine dimesylateAlmitrine bismesylateAlmitrineAlmitrine mesylate
Brand Name
VectarionDuxilDoxil
IUPAC Traditional name
almitrine
IUPAC name
6-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-2-N,4-N-bis(prop-2-en-1-yl)-1,3,5-triazine-2,4-diamine
Properties
No Data Available
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Molecule Details
Drug Groups
approved
Description
A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep. [PubChem]
Indication
For the treatment of chronic obstructive pulmonary disease.
Pharmacology
Almitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Affected Organisms
Humans and other mammals
External Links
Molecular Spectra
No Data Available
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References
No Data Available
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