Substance

ID:1134

Names and Identifiers
Brand Name
DesocortDesowenTridesilonDesilux
Synonyms
Desonide
IUPAC name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one
IUPAC Traditional name
desonide
Registration numbers
CAS Number
PubChem CID
PubChem SID
Properties
Physical Property
Hydrophobicity(logP)
1.4
Solubility
Practically insoluble
Molecule Details
Drug Groups
approved; investigational
Description
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. [PubChem]
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatose.
Pharmacology
Desonide is a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Affected Organisms
Humans and other mammals
Absorption
Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin may increase percutaneous absorption.
Molecular Spectra
No Data Available
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References
No Data Available
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