Substance
ID:1127
Names and Identifiers
IUPAC name
2-benzyl-4-(octahydro-1H-isoindol-2-yl)-4-oxobutanoic acid
Synonyms
Mitiglinide calcium hydratemitiglinideKAD-1229Mitiglinide
IUPAC Traditional name
mitiglinide calcium dihydrate
Brand Name
Glufast
Properties
Physical Property
Hydrophobicity(logP)
2.9
Solubility
0.0708 mg/mL [Predicted by ALOGPS]
Molecule Details
Drug Groups
approved; investigational
Description
Mitiglinide is a drug for the treatment of type 2 diabetes .Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) (K(ATP)) channels in pancreatic beta-cells.
Indication
For the treatment of type 2 diabetes.
Pharmacology
Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs. It is approved for use in Japan but has not yet gained FDA approval.
External Links
Molecular Spectra
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References
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