Substance
ID:110
Names and Identifiers
Synonyms
Gadodiamide hydrateGadodiamide
IUPAC Traditional name
gadolinium(3+) 2-[bis({2-[(carboxylatomethyl)[(methylcarbamoyl)methyl]amino]ethyl})amino]acetate hydrate
IUPAC name
gadolinium(3+) ion 2-[bis({2-[(carboxylatomethyl)[(methylcarbamoyl)methyl]amino]ethyl})amino]acetate hydrate
Brand Name
Omniscan
Properties
No Data Available
Click here to submit data
Molecule Details
Drug Groups
approved
Description
Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan. [Wikipedia]
Indication
For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues.
Affected Organisms
Humans and other mammals
Biotransformation
There is no detectable biotransformation or decomposition of gadodiamide.
Half Life
Two-compartment model with mean distribution and elimination half-lives (reported as mean ± SD) of 3.7 ± 2.7 minutes and 77.8 ± 16 minutes, respectively.
Elimination
Gadodiamide is eliminated primarily in the urine.
Distribution
* 200 ± 61 mL/kg
Clearance
* Renal cl=1.7 mL/min/kg
* Plasma cl=1.8 mL/min/kg
* Plasma cl=1.8 mL/min/kg
External Links
•
[RxList]
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data