CAS 372-47-4|3-fluoropyridine|3-fluoropyridine|3-Fluoropyridine|3-Fluoropyridine 98%|3-Fluoropyridine|3-氟吡啶

InChI=1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H

CELKOWQJPVJKIL-UHFFFAOYSA-N

H Acceptors

H Donor

LogD (pH = 5.5)

0.8976593

LogD (pH = 7.4)

0.89826757

Log P

0.8982753

Molar Refractivity

24.1175

Polarizability

9.114786

Polar Surface Area

12.89

Rotatable Bonds

Lipinski's Rule of Five

true

3-Fluoropyridine3-Fluoropyridine 98%3-Fluoropyridine3-氟吡啶

IUPAC Traditional name

Click here to submit data

PC4201

Tetrahedron, 39, 2009 (1983): with LDA lithiation is at the 2-position initially, however with longer reaction times the major product is the 4-litho derivative. Ask for other refs.

196665

Packaging
5 g in glass bottle

• Metallation with LDA appears to occur initially mainly at the 2-position, but after longer reaction times, the 4-lithio derivative is the major product: Tetrahedron, 39, 2009 (1983). For a more recent example of 4-lithiation, see: Heterocycles, 35, 151 (1994).

Names and Identifiers

Synonyms

3-Fluoropyridine3-Fluoropyridine 98%3-Fluoropyridine3-氟吡啶

IUPAC name

3-fluoropyridine

IUPAC Traditional name

3-fluoropyridine

Registration numbers

PubChem CID

MDL Number

PubChem SID

CAS Number

EC Number

Beilstein Number

Molecule Details

PC4201

Tetrahedron, 39, 2009 (1983): with LDA lithiation is at the 2-position initially, however with longer reaction times the major product is the 4-litho derivative. Ask for other refs.

Sigma Aldrich

196665

Packaging
5 g in glass bottle

References

PubChem Literature

From Data Sources

Bioactivity

PubChem BioAssay

GHS Pictograms

Acute toxicity (oral, dermal, inhalation), category 4

Skin irritation, category 2

Eye irritation, category 2

Skin sensitisation, category 1

Specific Target Organ Toxicity – Single exposure, category 3

Flammable gases, category 1

Flammable aerosols, categories 1,2

Flammable liquids, categories 1,2,3

Self-reactive substances and mixtures, Types B,C,D,E,F

Pyrophoric liquids, category 1

Pyrophoric solids, category 1

Self-heating substances and mixtures

Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3

Organic peroxides, Types B,C,D,E,F

GHS Signal Word

Danger

GHS Hazard statements

H225-H315-H319-H335

RID/ADR

UN 1993 3/PG 2

Hazard Class

Packing Group

Risk Statements

11-36/37/38

European Hazard Symbols

Irritant (Xi)

Flammable (F)

Personal Protective Equipment

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Safety Statements

16-26-36/37/39

7-26-33-37-60

German water hazard class

UN Number

1993

UN1993

GHS Precautionary statements

P210-P261-P305+P351+P338

P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A

Hydrophobicity(logP)

Molecule

ID:9971