CAS 76-03-9|Trichloroacetic acid 99%|trichloroacetic acid|trichloroacetic acid|TCA|Dow sodium inhibited|Acide trichloracetique|TRICHLOROACETIC ACID, 0.38 N SOLUTION|Acido tricloroacetico|TRICHLOROAC...

General Information

Structure

Molecular Formula

C₂HCl₃O₂

Molecular Mass

163.38714

Exact Mass

161.90421231

Charge

InChI

InChI=1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChIKey

YNJBWRMUSHSURL-UHFFFAOYSA-N

Canonic Smiles

OC(=O)C(Cl)(Cl)Cl

Isomeric Smiles

OC(=O)C(Cl)(Cl)Cl

Calculated Properties

JChem

Acid pKa

1.7156028

H Acceptors

H Donor

LogD (pH = 5.5)

-1.8084882

LogD (pH = 7.4)

-1.9973965

Log P

1.5290427

Molar Refractivity

28.1583

Polarizability

10.98023

Polar Surface Area

37.3

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Names and Identifiers

Synonyms

Trichloroacetic acid 99%TCADow sodium inhibitedAcide trichloracetiqueTRICHLOROACETIC ACID, 0.38 N SOLUTIONAcido tricloroaceticoTRICHLOROACETIC ACIDTRICHLOROACETIC ACID, ACSAceto-caustinTrichloressigsaeureTrichloroethanoic AcidKonestaVaritoxTRICHLOROACETIC ACID 0.60 N SOLUTION2,2,2-trichloroacetic acid脱保护三氯乙酸溶液Trichloroacetic acid三氯乙酸TRICHLOROACETIC ACID 0.18 N SOLUTIONTRICHLOROACETIC ACID, 0.49 N SOLUTIONTCA 脱保护溶液TRICHLOROACETIC ACID 6.1 N SOLUTIONTRICHLOROACETIC ACID 0.73 N SOLUTIONTCA DeblockDeblock trichloroacetic acid solution脱保护三氯乙酸溶液三氯乙酸溶液Trichloroacetic acid solutionDeblock trichloroacetic acid solutionTrichloroacetic acid, ACS三氯乙酸, ACS

IUPAC name

trichloroacetic acid

IUPAC Traditional name

trichloroacetic acid

Names and Identifiers

Registration numbers

CHEMBL

14053

Wikipedia Title

Trichloroacetic_acid

MDL Number

MFCD00004177

PubChem SID

249005502485844624900586248894601620787742489988224856470248742492489918624899909248628592488945924900373249002332486047224867684

Beilstein Number

CAS Number

KEGG ID

EC Number

PubChem CID

Merck Index

Registration numbers

Properties

Safety Information

Corrosive/Hygroscopic/Store under Argon

Hygroscopic

R:35

R35,R50/53

35-50/53

Properties

Related Proteins

No Data Available

Click here to submit data

Molecular Spectra

No Data Available

Click here to submit data

Molecule Details

MP Biomedicals

02152592

ACS Reagent Grade
Purity: ≥99.0%

02196058

0.73 N Solution
Approx. 12% (w/v)

02190521

Crystalline
Protein precipitation reagent

02196060

0.49 N Solution
Approx. 8% (w/v)

02196059

0.60 N Solution
Approx. 10% (w/v)

02196057

6.1 N Solution
Approx. 100% (w/v)

02196061

0.38 N Solution
Approx. 6.25% (w/v)

02196062

0.18 N Solution
Approx. 3% (w/v)

Wikipedia

Trichloroacetic_acid

Sigma Aldrich

T4885

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
1, 2 kg in glass bottle
500 g in glass bottle

T9159

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
100, 250, 500 g in glass bottle

T6399

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
1 kg in glass bottle
5, 100, 250, 500 g in glass bottle

T8657

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
1 kg in glass bottle
250, 500 g in glass bottle

251399

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

T0699

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation.Used as a decalcifier and fixative in microscopy.

T0324

Components
Contains 0.025% sodium azide as a preservative
Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation.Used as a decalcifier and fixative in microscopy.

91228

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Other Notes
Concentration of protein by quantitative precipitation1; Cytochemical demonstration of DNA with a thiazine dye2

91232

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

49948

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

30566

Application
Reagent used in the phosphite triester method of oligonucleotide synthesis for the cleavage of the 5′-protect ing group. Reagent is suitable for use on ABI, Beckman, Expedite synthesizers.
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation.Used as a decalcifier and fixative in microscopy.
General description
filtered through a 1 μm filter

31267

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Legal Information
PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH

91233

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

91230

T0199

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation.Used as a decalcifier and fixative in microscopy.

116114

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Packaging
100 g in glass bottle
2 kg in glass bottle

561932

Packaging
4×2.5, 4×4 L in glass bottle
View returnable container options.

522082

Application
Suitable for protein sequencing
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Packaging
100 g in glass bottle

27242

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

33731

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

PS34

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

442820

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

30-3905

30-3890

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Molecule Details

References

PubChem Literature

From Data Sources

• The acid and its Na salt (1:1) in DMF are also effective: Tetrahedron Lett., 33, 3435 (1992). Use of HMPA or DMI extends the scope to less reactive aldehydes: Synthesis, 327 (1990).

• Trihaloacetic acids react with aldehydes in DMSO at room temperature to give trihalomethyl carbinols: J. Chem. Soc., Perkin 2, 1247 (1984):

References

Bioactivity

PubChem BioAssay

Bioactivity

Names and Identifiers

Synonyms

IUPAC name

trichloroacetic acid

IUPAC Traditional name

trichloroacetic acid

Registration numbers

CHEMBL

14053

Wikipedia Title

Trichloroacetic_acid

MDL Number

MFCD00004177

PubChem SID

249005502485844624900586248894601620787742489988224856470248742492489918624899909248628592488945924900373249002332486047224867684

Beilstein Number

CAS Number

KEGG ID

EC Number

PubChem CID

Merck Index

Molecule Details

ACS Reagent Grade
Purity: ≥99.0%

02196058

0.73 N Solution
Approx. 12% (w/v)

02190521

Crystalline
Protein precipitation reagent

02196060

0.49 N Solution
Approx. 8% (w/v)

02196059

0.60 N Solution
Approx. 10% (w/v)

02196057

6.1 N Solution
Approx. 100% (w/v)

02196061

0.38 N Solution
Approx. 6.25% (w/v)

02196062

0.18 N Solution
Approx. 3% (w/v)

Wikipedia

Trichloroacetic_acid

Sigma Aldrich

T4885

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
1, 2 kg in glass bottle
500 g in glass bottle

T9159

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
100, 250, 500 g in glass bottle

T6399

T8657

Application
传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。
包装
1 kg in glass bottle
250, 500 g in glass bottle

251399

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

T0699

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation.Used as a decalcifier and fixative in microscopy.

T0324

91228

91232

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

49948

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

30566

31267

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Legal Information
PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH

91233

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

91230

T0199

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation.Used as a decalcifier and fixative in microscopy.

116114

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Packaging
100 g in glass bottle
2 kg in glass bottle

561932

Packaging
4×2.5, 4×4 L in glass bottle
View returnable container options.

522082

27242

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

33731

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

PS34

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

442820

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

30-3905

30-3890

Application
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

References

PubChem Literature

From Data Sources

• The acid and its Na salt (1:1) in DMF are also effective: Tetrahedron Lett., 33, 3435 (1992). Use of HMPA or DMI extends the scope to less reactive aldehydes: Synthesis, 327 (1990).

• Trihaloacetic acids react with aldehydes in DMSO at room temperature to give trihalomethyl carbinols: J. Chem. Soc., Perkin 2, 1247 (1984):

Bioactivity

PubChem BioAssay

Properties

Safety Information

Corrosive/Hygroscopic/Store under Argon

Hygroscopic

R:35

R35,R50/53

35-50/53

Molecule

ID:92076