• Biochem J. , 39 : 507 (1945).
• Biochem J. ,189 : 135 (1980).
• J. Invest. Dermatol. , 62 : 2 (1974).
• Ammonia/ammonium acetate to give 2,4-dinitroaniline: Org. Synth. Coll., 2, 221 (1943); or with ammonia gas in toluene in the presence of TBAB which improves the solubility of ammonia in the organic medium and accelerates the reaction: J. Chem. Soc., Chem. Commun., 1267 (1987). Benzyl mercaptan to give the thioether: Org. Synth. Coll., 5, 474 (1973). Iodide ion to give 2,4-dinitro-1-iodobenzene: Org. Synth. Coll., 5, 478 (1973). Nitrite in toluene (phase-transfer) to give 1,2,4-trinitrobenzene (caution!): J. Org. Chem., 56, 4967 (1991).
• The doubly-activated chloro-substituent is readily displaced by nucleophiles, e.g.:
Toxic (T)
Nature polluting (N)
