Molecule

726699 

Packaging
5, 25 g in glass bottle
Legal Information
ChiPros is a registered trademark of BASF SE

563382 

Packaging
1 g in glass bottle
Application
Reactant involved in:
• Diastereoselective Wadsworth-Emmons cyclopropanation for synthesis of quaternaty cyclopropyl esters1
• Synthesis of phenylethanolamine derivatives as β3-adrenergic receptor agonists2,3
• Stereoselective ring-opening for synthesis of β-aryloxy-substituted alcohols and amines4
• Synthesis of Biphenyl benzoic acid derivatives as β3-adrenergic receptor agonists5,6
• Synthesis of (S)-2-, 3-, and 4-chlorostyrene oxides with epoxide hydrolase7

440868 

Application
Key chiral synthon for the preparation of the potent antidiabetic and antiobesity agent CL-316,243, a benzodioxole-containing phenethanolamine.8 Ring opening of this chiral epoxide with amines produces amino alcohols which have been used as β-adrenergic agonists.9
Reactant involved in:
• Diastereoselective Wadsworth-Emmons cyclopropanation for synthesis of quaternaty cyclopropyl esters1
• Synthesis of phenylethanolamine derivatives as β3-adrenergic receptor agonists2,3
• Stereoselective ring-opening for synthesis of β-aryloxy-substituted alcohols and amines4
• Synthesis of Biphenyl benzoic acid derivatives as β3-adrenergic receptor agonists5,6
• Synthesis of (S)-2-, 3-, and 4-chlorostyrene oxides with epoxide hydrolase7

26008 

Other Notes
Chiral building block; preparation of a novel β-adrenergic agonist1,2