CAS 13057-17-5|Methoxymethyl bromide|溴甲基甲醚|BMME|bromo(methoxy)methane|Bromomethyl methyl ether|溴甲基甲基醚|methane, bromomethoxy-|Bromo(methoxy)methane|Bromomethyl methyl ether|bromo(methoxy)m...

General Information

Structure

Molecular Formula

C₂H₅BrO

Molecular Mass

124.9645

Exact Mass

123.95237678

Charge

InChI

InChI=1S/C2H5BrO/c1-4-2-3/h2H2,1H3

InChIKey

JAMFGQBENKSWOF-UHFFFAOYSA-N

Canonic Smiles

COCBr

Isomeric Smiles

O(CBr)C

Calculated Properties

JChem

H Acceptors

H Donor

LogD (pH = 5.5)

0.6137889

LogD (pH = 7.4)

0.6137889

Log P

0.6137889

Molar Refractivity

20.4685

Polarizability

8.11769

Polar Surface Area

9.23

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Names and Identifiers

Synonyms

Methoxymethyl bromide溴甲基甲醚BMMEBromomethyl methyl ether溴甲基甲基醚Bromo(methoxy)methaneBromomethyl methyl etherbromo(methoxy)methane

IUPAC name

bromo(methoxy)methane

IUPAC Traditional name

methane, bromomethoxy-

Names and Identifiers

Registration numbers

CAS Number

MDL Number

PubChem SID

PubChem CID

Beilstein Number

Registration numbers

Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

Sigma Aldrich

161756

Packaging
5, 25 g in glass bottle

Molecule Details

References

PubChem Literature

From Data Sources

• Reagent for protection of OH groups as their methoxymethyl (MOM) ethers. The group can be introduced in the presence of a base such as N-ethyldiisopropylamine: Tetrahedron Lett., 26, 6461 (1986); 30, 1971 (1989). Aryl acetates are converted directly into aryl methoxymethyl ethers in the presence of NaOMe in DMF: Synth. Commun., 29, 2217 (1999).

• For a review of the use of ɑ-monohalo ethers in synthesis, see: Synthesis, 1 (1995).

• A method for the ɑ-methylenation of lactones involves alkylation of the ɑ-lithio derivative, followed by elimination of methanol: J. Am. Chem. Soc., 102, 3964 (1980).

References

Bioactivity

PubChem BioAssay

Bioactivity

Names and Identifiers

Synonyms

Methoxymethyl bromide溴甲基甲醚BMMEBromomethyl methyl ether溴甲基甲基醚Bromo(methoxy)methaneBromomethyl methyl etherbromo(methoxy)methane

IUPAC name

bromo(methoxy)methane

IUPAC Traditional name

methane, bromomethoxy-

Registration numbers

CAS Number

MDL Number

PubChem SID

PubChem CID

Beilstein Number

Molecule Details

161756

Packaging
5, 25 g in glass bottle

References

PubChem Literature

From Data Sources

• For a review of the use of ɑ-monohalo ethers in synthesis, see: Synthesis, 1 (1995).

• A method for the ɑ-methylenation of lactones involves alkylation of the ɑ-lithio derivative, followed by elimination of methanol: J. Am. Chem. Soc., 102, 3964 (1980).

Bioactivity

PubChem BioAssay

Properties

Molecule

ID:75252